Raise Low Testosterone to Improve Sleep Study Concludes
Posted on July 13, 2008
Filed Under testosterone |
From Journal of Clinical Endocrinology and Metabolism, MD - Jul 10, 2008
Over thirteen hundred males over sixty five were divided in two groups: Those with more that 250 ng/dl total testosterone levels and those below that level.
Men with lower testosterone levels had lower sleep efficiency, with increased nocturnal awakenings and less time in slow-wave sleep as well as a higher apnea-hypopnea index and more sleep time with O2 saturation levels below 90%. Low testosterone levels were associated with overweight, and all significant associations were attenuated or absent after adjusting for body mass index or waist circumference. In a post hoc analysis in men with higher body mass index (>27 kg/m2), testosterone was significantly associated with more periods awake after sleep onset and lower sleep efficiency.
Conclusion: Low total testosterone levels are associated with less healthy sleep in older men. This association is largely explained by adiposity. Clinical trials are necessary to determine whether body weight acts directly or indirectly (via low testosterone) in the causal pathway for sleep-disordered breathing in older men.
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